How to Email a Supplement Manufacturer (Your First RFQ, Step by Step)
By Greg Huang, founder since 2009 in the dietary supplement and nutrition industry
Your first RFQ to a supplement manufacturer: the five things to put in it, the three questions to ask, and how to follow up without being a pest.
Chapters
Transcript
Transcript is taken from the video's English captions, with paragraph breaks added at the chapters. Text in square brackets is shown on screen, not spoken.
There are more than a hundred supplement manufacturers in the United States. It's tempting to start by asking for a price, but a price request on its own tells a manufacturer very little about you. The first real message you send is called an RFQ, a request for quote, and it goes a long way toward deciding which manufacturers take your brand seriously. So here's what to put in plain English and the step that's easiest to skip.
An RFQ is also your first read on the people who will make your product. How fast they reply, how clearly they explain their minimums, and whether they ask smart questions back gives you a good preview of what it's like to work with them because you're choosing a partner you'll make many batches with. A vague RFQ tends to get a vague reply or none at all. So the goal of your first one is to give every manufacturer enough detail that the quotes you get back compare the same thing.
There are five things to put in it. First, what the product is, the form, whether that's a capsule, gummy, or powder, the main ingredients, and the dose you're aiming for. Second, how much. Your first run size and your rough yearly volume. Manufacturers price by scale, so a real number gets you a real quote instead of a guess. Then, certifications you need, the packaging, and when you want the product in hand. You don't send your formula just yet. That comes later, after you both sign a simple non-disclosure agreement.
Along with those five things, ask three questions. What is your minimum order, and how does the price change at higher volumes? What is your real lead time from approved formula to product in your hands? The third one is easy to miss. How do you confirm the identity of every ingredient before you use it? Federal rules require that step on every incoming dietary ingredient. [On screen: Exemption by FDA petition: 21 CFR §111.75(a)(1)(ii).] A good manufacturer answers that plainly, and a vague answer there is the clearest warning sign you'll get. Also, ask for a certificate of analysis for your own batch and which tests were actually run on it, because a generic document from a supplier doesn't tell you about your product.
The last step is the follow-up. It's easy to send one RFQ and then just wait. If you don't hear back, send a short, polite nudge or two after that first message.
Your first RFQ won't be perfect, and it doesn't need to be. Make it specific. Send a follow-up, and the quotes that come back will be much easier to compare. The full RFQ guide with a checklist you can copy and a directory of manufacturers to send them to is linked below. Thanks for watching.
Sources
- FDA 2007 dietary supplement cGMP rule — 72 FR 34920, Table 20
- IBISWorld — Vitamin & Supplement Manufacturing in the US, number of businesses (2026)
- 21 CFR §111.75 — Identity Testing
- 21 U.S.C. §342(g) — cGMP authority for dietary supplements
- American Purchasing Society — writing an RFQ
- Superior Supplement Manufacturing — FAQ (minimums)
- Reliance Vitamin — contract manufacturing (quotes)
- Summit Rx — low-MOQ vs. large-scale manufacturers (per-unit cost)
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