Wellmune®
baker's yeast beta 1,3/1,6 glucan
Beta GlucanLast reviewed: July 11, 2026
Medical & Industry Advisor: Dr. James Pendleton, ND
Answer
Availability
We have not verified a current supply status for this ingredient. Unknown is our default: we publish a status only with dated evidence. If you have first-hand sourcing information, use the correction link below.
Owner and access
- Owner
- Kerry Group (site)
- Access model
- Licensed program
What it is
- Yeast beta-glucan brand within Kerry's ProActive Health portfolio. [wellmune.com]
Spec parameters buyers should demand
What to ask for on the certificate of analysis and spec sheet. Identity, quality, and regulatory parameters only. This is not advice about efficacy.
| Parameter | What to ask | Why it matters |
|---|---|---|
| Beta-glucan content and source organism | Request the certificate of analysis stating beta-1,3/1,6-glucan content and confirming the source organism is baker's yeast (Saccharomyces cerevisiae). The ingredient's US GRAS and EU Novel Food records characterize it as a baker's-yeast beta-1,3/1,6-glucan.[EFSA Scientific Opinion on yeast beta-glucans as a Novel Food, EFSA Journal 2011;9(5)] | Beta-glucans from different sources have different linkage structures, so the source organism and the 1,3/1,6 linkage are what identify this specific material. |
| Identity verification | Confirm the manufacturer runs at least one validated identity test on each incoming lot, as 21 CFR 111.75(a)(1) requires for every dietary ingredient.[21 CFR 111.75(a)(1) — identity test required for each dietary ingredient] | Identity testing is a federal manufacturing requirement, and a certificate that names the method is the record your own quality file needs. |
| Glucan linkage specification | Ask the CoA to state that the material is a beta-1,3/1,6-glucan (the yeast cell-wall structure) rather than a beta-1,3/1,4-glucan (the oat/barley structure), and request the method used to determine linkage.[EFSA Scientific Opinion, EFSA Journal 2011;9(5)] | The 1,3/1,6 versus 1,3/1,4 linkage is the structural difference between yeast and cereal glucans, so specifying it is how you rule out a source substitution under the same 'beta-glucan' name. |
| US and EU regulatory footing | Ask for the regulatory documentation on file: baker's-yeast beta-glucan has an FDA GRAS notice and EU Novel Food authorization. Request the specific references.[wellmune.com] | The GRAS and Novel Food records establish the ingredient's standing in both markets, which matters for products sold internationally. |
QC and testing considerations
- Every dietary ingredient must pass at least one validated identity test before use (21 CFR 111.75(a)(1)). Confirm your manufacturer runs identity testing on each incoming lot. [21 CFR 111.75(a)(1)]
- 'Beta-glucan' names several different molecules; confirm the CoA specifies baker's-yeast (Saccharomyces cerevisiae) beta-1,3/1,6-glucan so an oat, barley, or mushroom glucan is not substituted under the same category name. [EFSA Scientific Opinion, EFSA Journal 2011;9(5)]
- Request the FDA GRAS notice reference and EU Novel Food authorization so the regulatory record travels with the material, especially for products sold in multiple markets. [wellmune.com]
Further reading: How to read a certificate of analysis and third-party supplement testing.
Reference list
- EFSA Scientific Opinion on the safety of yeast beta-glucans as a Novel Food ingredient, EFSA Journal 2011;9(5):2137 Regulatory
- 21 CFR Part 111 — Current Good Manufacturing Practice for dietary supplements (identity testing at 111.75) Regulatory
- Wellmune (Kerry Group) — branded baker's-yeast beta-1,3/1,6-glucan, owner site Owner technical
A reference list is not claim substantiation. Under the FTC's Health Products Compliance Guidance (December 2022), marketing claims about a finished product require competent and reliable scientific evidence, typically randomized, controlled human clinical testing. Responsibility for substantiating product claims rests with the brand.
Manufacturers with stated capability
No manufacturer has a listed capability for this ingredient yet. Listings are positive-only: an entry states a manufacturer can run the ingredient, never that one cannot.
Run this ingredient? Request inclusion.
Further reading
The decision framework behind this reference: five checkable criteria for choosing between a branded ingredient and its generic form.
What this page does not tell you
- Whether the owner will license your specific product or accept a new account.
- Pricing, minimum order volumes, or contract terms.
- Anything about efficacy. This is an identity and sourcing reference.
Prefills the ingredient into the RFQ Spec Builder. You enter your own formula; the tool formats it into a spec sheet.
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