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Gnosis by Lesaffre

Desio, Italy

Profile updated: April 2, 2026

Gnosis by Lesaffre is a biotechnology company specializing in fermentation-derived active ingredients, probiotics, and nutritional yeasts. Originally founded in 1989 as Gnosis S.p.A. in Desio, Italy (near Milan), the company was fully acquired by Lesaffre in 2018. Gnosis operates GMP manufacturing sites in Sant Antonino, Switzerland and Pisticci, Italy, with commercial offices in the US and China. The parent company Lesaffre is the world's largest yeast producer with EUR 2 billion in annual revenue. Key ingredients include vitaMK7 (naturally fermented vitamin K2 as MK-7), Quatrefolic (5-MTHF folate), and LifeinU L.rhamnosus GG probiotic. Gnosis has a joint venture with ADM (Red Star Yeast) in the United States.

Directory ListingRecords Reviewed

Public records and independent sources have been reviewed.

What this means →

Min. Order

Not publicly disclosed

Lead Time

Not publicly disclosed

Product Types

Fermentation-Derived Active Ingredients, vitaMK7 (Vitamin K2 as MK-7), Quatrefolic (5-MTHF Folate), Probiotics (LifeinU L.rhamnosus GG), Nutritional Yeasts, S-Adenosyl-L-Methionine (SAMe)

Capabilities

Fermentation-Based Manufacturing, GMP Manufacturing (Switzerland & Italy), Branded Ingredient Development, Clinical Research Programs, US Commercial Office, Red Star Yeast JV with ADM (US)

Certifications

0 of 1 certification independently confirmed. What this means

Key Regulatory Concepts

Dietary supplement manufacturers must comply with 21 CFR Part 111 (Current Good Manufacturing Practice for dietary supplements). This includes requirements for personnel, facilities, equipment, production, laboratory operations, and record-keeping.

Review Notes

Italian biotechnology company founded 1989, headquartered in Desio (near Milan). Fully acquired by Lesaffre (world's largest yeast producer, EUR 2B revenue) in 2018. GMP manufacturing in Switzerland (Sant Antonino) and Italy (Pisticci). US presence via commercial office and Red Star Yeast joint venture with ADM. Key branded ingredients: vitaMK7, Quatrefolic, LifeinU. NutraIngredients, Nutritional Outlook, and Food Ingredients First confirm acquisition and company profile. Ingredients Insight listing confirms operational structure.

Sources

Disclosures

  • No material connection exists between Inventory Ready and this company

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