JBSL-USA (Japan Bio Science Laboratory)
Walnut Creek, California
Profile updated: April 2, 2026
JBSL-USA is the US office of Japan Bio Science Laboratory (JBSL), founded in 1974 and headquartered in Osaka, Japan. JBSL is the pioneer of nattokinase research and in 1998 was the first company in the world to isolate and market this unique fibrinolytic enzyme. Their flagship ingredient, NSK-SD nattokinase, is fermented using JBSL's patented strain of Bacillus subtilis natto and is the only nattokinase with published identity, safety, and efficacy studies. NSK-SD has self-affirmed GRAS status in the US and novel food approval in Europe. The ingredient is supported by 50+ published studies including 30+ human clinical trials demonstrating cardiovascular and circulatory health benefits.
Directory Listing — Records Reviewed
Public records and independent sources have been reviewed.
What this means →Min. OrderMOQ (Minimum Order Quantity)The smallest production run a manufacturer will accept for an order.
Not publicly disclosed
Lead TimeLead TimeThe time from order placement to finished product delivery.
Not publicly disclosed
Product Types
NSK-SD Nattokinase (Fibrinolytic Enzyme), Patented Bacillus subtilis natto Fermentation
Capabilities
Nattokinase Pioneer (First to Market, 1998), Patented Bacillus subtilis natto Fermentation, Branded Ingredient Supply (NSK-SD), Self-Affirmed GRAS (US), EU Novel Food Approved, Clinical Research Programs (50+ Studies, 30+ Human Trials)
Certifications
0 of 1 certification independently confirmed. What this means
Key Regulatory Concepts
Dietary supplement manufacturers must comply with 21 CFR Part 111 (Current Good Manufacturing Practice for dietary supplements). This includes requirements for personnel, facilities, equipment, production, laboratory operations, and record-keeping.
Review Notes
US office of Japan Bio Science Laboratory (Osaka, founded 1974). Pioneer of nattokinase — first to isolate and market (1998). NSK-SD is the only nattokinase with published identity, safety, and efficacy studies. 50+ studies, 30+ human clinicals. Self-affirmed GRAS (US), EU novel food approved. Nutraceuticals World covered 50th anniversary. WholeFoods Magazine golden anniversary coverage. New Hope Network covered bioavailability study. NIE Magazine profiled Vincent Hackel. NSK-SD.info dedicated ingredient education site.
Sources
- JBSL-USA Official Website — About(2026-04-02)
- Nutraceuticals World — JBSL Japan Celebrates 50th Anniversary(2026-04-02)
Disclosures
- No material connection exists between Inventory Ready and this company
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