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Mitsubishi Gas Chemical — BioPQQ

Tokyo, Japan

Profile updated: April 2, 2026

Mitsubishi Gas Chemical Company, Inc. is a Japanese chemical manufacturer headquartered in Tokyo, Japan. Their BioPQQ brand produces pyrroloquinoline quinone (PQQ) disodium salt through a proprietary bacterial fermentation process. BioPQQ is the only PQQ ingredient to have received FDA New Dietary Ingredient (NDI) notification (2008), FDA GRAS determination (GRN 641 and 701), and European Food Safety Authority (EFSA) approval as a Novel Food ingredient. While alternative PQQ suppliers now exist (PureQQ, NutriPQQ, Chinese manufacturers), BioPQQ maintains the strongest regulatory position globally. PQQ is used in cognitive health and mitochondrial support supplements. BioPQQ is distributed in the US through MIFI USA.

Directory ListingRecords Reviewed

Public records and independent sources have been reviewed.

What this means →

Min. Order

Not publicly disclosed

Lead Time

Not publicly disclosed

Product Types

BioPQQ (Pyrroloquinoline Quinone Disodium Salt), MGCPQQ (European Brand Name), PQQ for Cognitive Health Supplements, PQQ for Mitochondrial Support Supplements

Capabilities

Proprietary PQQ Fermentation Manufacturing, FDA NDI Notification (2008, First PQQ NDI), FDA GRAS Determination (GRN 641, GRN 701), EU Novel Food Approved (EFSA Evaluated), US Distribution via MIFI USA

Certifications

0 of 1 certification independently confirmed. What this means

Key Regulatory Concepts

Dietary supplement manufacturers must comply with 21 CFR Part 111 (Current Good Manufacturing Practice for dietary supplements). This includes requirements for personnel, facilities, equipment, production, laboratory operations, and record-keeping.

Review Notes

Japanese chemical manufacturer, Tokyo HQ. BioPQQ is the first and only PQQ with FDA NDI notification (2008), GRAS determination (GRN 641, 701), and EFSA Novel Food approval. Proprietary fermentation process. Competitors now exist but lack equivalent regulatory dossier. US distribution via MIFI USA. BioPQQ.com and FDA GRAS notice (public document) confirm regulatory status and supplement market supply.

Sources

Disclosures

  • No material connection exists between Inventory Ready and this company

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