Con-Cret®
creatine hydrochloride (creatine HCl)
CreatineLast reviewed: July 9, 2026
Medical & Industry Advisor: Dr. James Pendleton, ND
Answer
Availability
We have not verified a current supply status for this ingredient. Unknown is our default: we publish a status only with dated evidence. If you have first-hand sourcing information, use the correction link below.
Owner and access
- Owner
- Vireo Systems, Inc. (site)
- Access model
- Licensed program
What it is
- Creatine hydrochloride brand made in the USA; brand site styles the mark CON-CRĒT®. [con-cret.com]
Spec parameters buyers should demand
What to ask for on the certificate of analysis and spec sheet. Identity, quality, and regulatory parameters only. This is not advice about efficacy.
| Parameter | What to ask | Why it matters |
|---|---|---|
| Assay (creatine content) and salt basis | Request the certificate of analysis, the assay method, and whether the number is reported as creatine hydrochloride or as creatine base. There is no separate pharmacopeial monograph for creatine HCl, so the CoA method and basis are the reference; the USP creatine monograph is the reference for the creatine moiety's identity.[con-cret.com — Creatine HCl FAQ] | A salt-form ingredient can be quoted on different bases; a stated method and basis keep the assay comparable and avoid double-counting the hydrochloride weight. |
| Identity verification | Confirm the manufacturer runs at least one validated identity test on each incoming lot, as 21 CFR 111.75(a)(1) requires for every dietary ingredient.[21 CFR 111.75(a)(1) — identity test required for each dietary ingredient] | Identity testing is a federal manufacturing requirement; a CoA that names the identity method is the paper trail your own quality file needs. |
| Salt form and solubility | Confirm the material is creatine hydrochloride (creatine conjugated with hydrochloric acid), a more water-soluble salt than creatine monohydrate, and ask for the patent and any dosing-basis notes the owner supplies.[con-cret.com — Creatine HCl FAQ] | The salt form changes solubility and the per-gram creatine basis; both belong on the spec sheet so your formula and label math are correct. |
| Banned-substance certification | For sports and team-channel products, ask whether the material is produced in an NSF-certified facility and whether finished product can carry NSF Certified for Sport. The owner states its domestic facility is NSF certified.[con-cret.com — Creatine HCl FAQ] | Banned-substance assurance is a channel requirement for many buyers and is verified at the facility and finished-product level, not by the ingredient name. |
QC and testing considerations
- Every dietary ingredient must pass at least one validated identity test before use (21 CFR 111.75(a)(1)). Confirm identity testing is run on each incoming lot of the hydrochloride salt, not only at supplier qualification. [21 CFR 111.75(a)(1)]
- Creatine converts to creatinine in the presence of water and heat, so the dry powder is the stable form. For any liquid or gummy format, test the finished product for both creatine content and creatinine, not just the incoming raw material. [USP-NF Creatine monograph]
- Because the assay can be reported on the hydrochloride or the creatine-base basis, reconcile the CoA basis with your label declaration before the run so the finished-product creatine claim is supportable. [con-cret.com — Creatine HCl FAQ]
Further reading: How to read a certificate of analysis and third-party supplement testing.
Reference list
- USP-NF Creatine monograph — identity and assay reference for the creatine moiety Pharmacopeia
- 21 CFR Part 111 — Current Good Manufacturing Practice for dietary supplements (identity testing at 111.75) Regulatory
- con-cret.com — Creatine HCl FAQ (owner technical documentation) Owner technical
A reference list is not claim substantiation. Under the FTC's Health Products Compliance Guidance (December 2022), marketing claims about a finished product require competent and reliable scientific evidence, typically randomized, controlled human clinical testing. Responsibility for substantiating product claims rests with the brand.
Manufacturers with stated capability
No manufacturer has a listed capability for this ingredient yet. Listings are positive-only: an entry states a manufacturer can run the ingredient, never that one cannot.
Run this ingredient? Request inclusion.
Related ingredients in this class
Reference navigation, not a recommendation. Forms and specs differ; evaluate against the criteria on the ingredient reference index.
Further reading
The decision framework behind this reference: five checkable criteria for choosing between a branded ingredient and its generic form.
What this page does not tell you
- Whether the owner will license your specific product or accept a new account.
- Pricing, minimum order volumes, or contract terms.
- Anything about efficacy. This is an identity and sourcing reference.
Prefills the ingredient into the RFQ Spec Builder. You enter your own formula; the tool formats it into a spec sheet.
Con-Cret® (styled CON-CRĒT®) is a registered trademark of Vireo Systems, Inc. Inventory Ready is not affiliated with, licensed by, or endorsed by the trademark owner.
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