Creavitalis®
creatine monohydrate
CreatineLast reviewed: July 9, 2026
Medical & Industry Advisor: Dr. James Pendleton, ND
Answer
Availability
Alzchem reports quickly increasing demand for Creapure® and Creavitalis® is outstripping supply, limiting its ability to fully supply new inquiries (trade press, May 2026). Two US contract manufacturers told Inventory Ready in June 2026 they were unable to open new Creavitalis® accounts. Alzchem's new production capacity is expected to begin commissioning in late 2027.
- NutraIngredients:Alzchem confronts capacity pressures (2026-05-28)
- Alzchem:~EUR 120M creatine investment program (2025-12-16)
Owner and access
- Owner
- Alzchem Group AG (site)
- Access model
- Licensed program
What it is
- Alzchem's creatine monohydrate brand positioned for food and broader health applications, produced in Germany alongside Creapure®. [creavitalis.com]
Spec parameters buyers should demand
What to ask for on the certificate of analysis and spec sheet. Identity, quality, and regulatory parameters only. This is not advice about efficacy.
| Parameter | What to ask | Why it matters |
|---|---|---|
| Assay (creatine content) | Request the certificate of analysis and the assay method. Pharmacopeial creatine is defined as not less than 98.0% and not more than 102.0% creatine on the dried basis (USP-NF); confirm the CoA names the method used.[USP-NF Creatine monograph] | The assay is the identity-and-strength number a spec sheet stands on, and a stated pharmacopeial method makes results comparable across suppliers. |
| Identity verification | Confirm the manufacturer runs at least one validated identity test on each incoming lot, as 21 CFR 111.75(a)(1) requires for every dietary ingredient.[21 CFR 111.75(a)(1) — identity test required for each dietary ingredient] | Identity testing is a federal manufacturing requirement; a CoA that names the identity method is the paper trail your own quality file needs. |
| Synthesis-route impurity limits | Request limits and results for dicyandiamide (DCD), dihydrotriazine (DHT), and creatinine. The referenced specification is creatinine not more than 100 mg/kg, DCD not more than 50 mg/kg, and DHT not detectable.[EFSA Scientific Panel opinion on creatine monohydrate] | These are byproducts of the sarcosine-plus-cyanamide route; the limits are the accepted purity ceiling for the ingredient. |
| Particle-size grade | Specify the grade you need. Creavitalis® is offered micronized for solubility and blend uniformity, with a larger-particle SG grade for capsule filling; request the particle-size distribution.[creavitalis.com — micronized creatine monohydrate and SG capsule-filling grade] | Particle size drives how the powder dissolves and how evenly it blends; it is a formulation spec, not a quality defect, so it belongs on the RFQ. |
QC and testing considerations
- Every dietary ingredient must pass at least one validated identity test before use (21 CFR 111.75(a)(1)). Confirm identity testing is run on each incoming lot, not only at supplier qualification. [21 CFR 111.75(a)(1)]
- Synthetic creatine can carry dicyandiamide, dihydrotriazine, and creatinine from its manufacturing route. Ask for a certificate of analysis that reports these byproducts against the accepted limits. [EFSA Scientific Panel opinion on creatine monohydrate, EFSA Journal 2004;36]
- Creatine converts to creatinine in the presence of water and heat, so the anhydrous powder is the stable form. For liquid or gummy formats, test the finished product for both creatine content and creatinine. [EFSA Scientific Panel opinion on creatine monohydrate]
Further reading: How to read a certificate of analysis and third-party supplement testing.
Reference list
- USP-NF Creatine monograph — identity, assay, and impurity specifications Pharmacopeia
- 21 CFR Part 111 — Current Good Manufacturing Practice for dietary supplements (identity testing at 111.75) Regulatory
- EFSA Scientific Panel opinion on creatine monohydrate, EFSA Journal 2004;36 Regulatory
- creavitalis.com — product technical page (grades, provenance) Owner technical
A reference list is not claim substantiation. Under the FTC's Health Products Compliance Guidance (December 2022), marketing claims about a finished product require competent and reliable scientific evidence, typically randomized, controlled human clinical testing. Responsibility for substantiating product claims rests with the brand.
Manufacturers with stated capability
No manufacturer has a listed capability for this ingredient yet. Listings are positive-only: an entry states a manufacturer can run the ingredient, never that one cannot.
Run this ingredient? Request inclusion.
Related ingredients in this class
Reference navigation, not a recommendation. Forms and specs differ; evaluate against the criteria on the ingredient reference index.
Further reading
The decision framework behind this reference: five checkable criteria for choosing between a branded ingredient and its generic form.
What this page does not tell you
- Whether the owner will license your specific product or accept a new account.
- Pricing, minimum order volumes, or contract terms.
- Anything about efficacy. This is an identity and sourcing reference.
Prefills the ingredient into the RFQ Spec Builder. You enter your own formula; the tool formats it into a spec sheet.
Creavitalis® is a registered trademark of Alzchem Group AG. Inventory Ready is not affiliated with, licensed by, or endorsed by the trademark owner.
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