Best Formulations (Sirio Americas)

Best Formulations has manufactured dietary supplements and softgels from City of Industry, California since 1984. The company was acquired by Sirio Pharma in 2023 and now operates as Sirio Americas. This gives them access to a global network spanning Asia and Europe. Best Formulations is one of the largest plant-based softgel manufacturers in the United States. They specialize in difficult paste-style softgel formulas and probiotic handling. The company holds an FDA drug license, which is a higher regulatory standard than standard dietary supplement registration. Their four Southern California facilities total over 120,000 sq ft. They also hold NPA GMP certification and NSF GMP for Sport designation, making them suitable for sports nutrition brands. The Sirio acquisition brings institutional-grade resources but may add corporate complexity for smaller brands.