Best Formulations (Sirio Americas)

Best Formulations has manufactured dietary supplements and softgels from City of Industry, California since 1984. The company was acquired by Sirio Pharma in 2023 and now operates as Sirio Americas. This gives them access to a global network spanning Asia and Europe. Best Formulations is one of the largest plant-based softgel manufacturers in the United States. They specialize in difficult paste-style softgel formulas and probiotic handling. The company holds an FDA drug license, which is a higher regulatory standard than standard dietary supplement registration. Their four Southern California facilities total over 120,000 sq ft. Their NSF GMP registration is confirmed in the NSF public directory under NSF 306, Section 6; an NPA GMP certification and a Sport designation are self-reported and not confirmable in a public register. The Sirio acquisition brings institutional-grade resources but may add corporate complexity for smaller brands.

Directory Listing · Certifications Confirmed

One or more certifications independently confirmed via public registries.

What this means →

City of Industry, California

MOQ: Not publicly disclosed
LEAD TIME: Not publicly disclosed

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Editor’s call

NSF GMP registration independently confirmed via the NSF public directory (re-read 2026-08-20): Sirio Nutrition (California) LLC, City of Industry, listed under NSF 306, Section 6. A Sport designation was previously recorded here as independently confirmed; it is NOT confirmable and has been withdrawn (the directory's Program=306GMP filter returns the same result set as a known-bad control, so it cannot discriminate a Sport listing, and the listing itself carries no Sport marker). NPA GMP certification is self-reported and not found in NPA public directory (parent Sirio Pharma is listed). All other certifications (FDA Drug License, cGMP, FDA Registration) are self-reported. The 2023 acquisition by Sirio Pharma (Shenzhen-listed, 300791.SZ) introduces a question that matters to brands evaluating long-term partnerships: how much operational independence does the U.S. facility retain?

Greg
founder of Inventory Ready · sole reviewer

§1Editorial assessment

cGMP (Current Good Manufacturing Practice)FDA Facility Registration MOQ (Minimum Order Quantity)NSF International Formulation Dosage Form

§2Our review

The six checks in our review, applied before any name appears in the directory. Each check is auto-derived from public evidence on this profile.

§3Certifications

1 of 5 certifications independently confirmed. What this means

FDA Drug License(Self-Reported)cGMP Compliant(Self-Reported)NPA GMP Certified(Self-Reported)NSF GMP Registered(Confirmed)FDA Registered(Self-Reported)

§4Capability matrix

PRODUCT TYPES: Softgels · Tablets · Capsules · Powders · Gummies · Liquids
CAPABILITIES: Contract Manufacturing · Custom Formulation · Plant-Based Softgels · Probiotic Handling · R&D
DOSAGE FORMS: capsules · gummies · liquids · powders · softgels · tablets

§5Sources

Best Formulations - Official Website(2026-03-12)
NSF GMP for Sport Designation (New Hope)(2026-03-12)
Sirio Pharma Acquisition (Nutritional Outlook)(2026-03-12)
NSF International GMP Directory(2026-03-18)

Dietary supplement manufacturers must comply with 21 CFR Part 111 (Current Good Manufacturing Practice for dietary supplements). This includes requirements for personnel, facilities, equipment, production, laboratory operations, and record-keeping.

Disclosures

Best Formulations is a subsidiary of Sirio Pharma Co., Ltd. (publicly traded: 300791.SZ)

The connection map between Best Formulations (Sirio Americas) and other vendors, capabilities, and certifications is in the manufacturer atlas.

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