CONTRACT MANUFACTURING
Natura-Genics
Chino, California
Contract manufacturer of vitamin, mineral, probiotic, amino acid, enzyme and herbal extract supplements.
MOQ
Not publicly disclosed
LEAD TIME
Not publicly disclosed
Last reviewed: October 20, 2026 | Next review: January 15, 2027
54 assessed manufacturers across 7 categories in California. Each profile is independently evaluated using our published assessment method.
California accounts for roughly 15% of the active listings in our directory. Most of those listings are in Southern California: contract manufacturers, packaging providers, flavor houses, testing labs, and ingredient suppliers from Los Angeles and the Inland Empire through Orange County to San Diego County.
Three features of California matter for sourcing. First, port proximity. The Port of Long Beach's facts page ranks it, with the Port of Los Angeles, as the world's ninth-busiest port complex by container volume. A manufacturer near these ports can shorten transit for imported botanicals and other raw materials.
Source: Port of Long Beach, Facts at a Glance (read October 2026)
Second, people. California has university food science programs (UC Davis and Cal Poly among them) and a large pharmaceutical and biotech sector, both sources of quality assurance, regulatory, and formulation staff.
Third, industry infrastructure. Natural Products Expo West is held each year at the Anaheim Convention Center, and testing labs and ingredient suppliers operate alongside the state's manufacturers.
California-based manufacturers include Robinson Pharma (Santa Ana; its website gives its facilities' combined floor space as approaching one million square feet) and GMP Laboratories of America (Anaheim; two facilities totaling over 100,000 square feet).
Facility data: robinsonpharma.com, gmplabs.com (read October 2026)
California adds state requirements to the federal cGMP regulations. Which of those below apply depends on what you make, where you make it, and the size of your business. SB 1033 is a bill, not law.
Regulatory requirements change. Verify current requirements directly with CDPH and OEHHA before making compliance decisions.
Prop 65 requires businesses with 10 or more employees to warn California consumers about significant exposures to listed chemicals. Lead, cadmium, inorganic arsenic compounds, and mercury and mercury compounds are on the list. OEHHA publishes safe-harbor levels for many listed chemicals; an exposure at or below the level needs no warning.
| Heavy Metal | Safe Harbor Level | Type |
|---|---|---|
| Lead (Pb) | 0.5 mcg/day | MADL (reproductive) |
| Cadmium (Cd) | 4.1 mcg/day (oral) | MADL (reproductive) |
| Arsenic (inorganic arsenic compounds) | 10 mcg/day (routes other than inhalation) | NSRL (cancer) |
| Mercury (Hg) | No safe-harbor level on OEHHA's list | Evaluate per product |
Source: OEHHA, Proposition 65 NSRLs and MADLs (read October 2026)
21 CFR Part 111 sets no numeric limits for these metals; it requires each manufacturer to set its own limits on contamination (21 CFR 111.70(e)). A product that passes federal testing may still require a Prop 65 warning label in California.
Signed into law by Governor Newsom in October 2025 (Chapter 602, Statutes of 2025), SB 646 requires, starting January 1, 2027, the manufacturer of a bulk or packaged prenatal multivitamin that is sold, manufactured, delivered, held, or offered for sale in California to test a representative sample of each lot for arsenic, cadmium, lead, and mercury at a “proficient laboratory”. The law defines that by a list of criteria, of which ISO/IEC 17025:2017 accreditation is one; an in-house laboratory can qualify if it meets them all. Brand owners must also publish the results and other specified information online. For a product sold in a retail store and shipped to retailers on or after January 1, 2027, the outermost package must say “For information about heavy metal testing on this product, visit” followed by the web address of that information. For a product sold online or directly to consumers and shipped to consumers on or after that date, the product details page must carry the same statement followed by a hyperlink. A product sold both ways needs both. From January 1, 2030, a prenatal multivitamin without those statements may not be sold in California. The full disclosure rules are in section 110424.2. The law applies specifically to prenatal multivitamins, not all dietary supplements.
Source: CA Legislative Information: SB 646 (Health and Safety Code sections 110424 to 110424.3, read October 2026)
SB 1033 has not been signed into law and is not currently advancing. It passed the Senate Health Committee on March 26, 2026 with bipartisan support (10-0) and the Senate Environmental Quality Committee on April 22, 2026 (4-1), but after referral to the Senate Appropriations Committee it was placed on the suspense file on May 4, 2026 and held in committee under submission on May 14, 2026. A bill held under submission does not move forward unless the committee takes it up again. As proposed, it would require manufacturers of bulk and packaged protein products sold in California to test each lot for arsenic, cadmium, lead, and mercury, publicly disclose results, and prohibit sale of non-compliant products, with a proposed effective date of January 1, 2028. These requirements are not current law.
Legislative status: held in Senate Appropriations Committee (suspense file, under submission) since May 14, 2026, with no later action (as of October 2026)
California Health and Safety Code section 110460 requires businesses that manufacture, repack, label, or warehouse processed food in the state to register with the California Department of Public Health (CDPH). The Processed Food Registration is the firm's basic health permit, and CDPH lists dietary supplements among the products it covers. This registration is in addition to federal FDA food facility registration. If your manufacturer, packer, or labeler is located in California, confirm it holds a current PFR.
Source: CDPH, procedure for obtaining a PFR and Processed Food Registration (read October 2026)
SB 54 (the Plastic Pollution Prevention and Packaging Producer Responsibility Act) creates an extended producer responsibility program for packaging sold in California. Under CalRecycle's guidance, a producer must join the plan of the approved producer responsibility organization (Circular Action Alliance), apply to comply on its own, or obtain a small producer exemption. Producers with gross annual sales under $1 million may apply to be exempt from most reporting and fee requirements, but still need all the packaging they sell to be recyclable or compostable by 2032. Ask your packaging provider about SB 54 for your specific packaging format.
Source: CalRecycle: SB 54 producer guidance and exemptions and exclusions (read October 2026)
If you need a small first run, match your volume to a partner whose minimum fits before you request quotes.
The following table shows minimum order quantities that two California-based manufacturers publish on their own websites. Not all of these companies are in the Inventory Ready assessed directory.
| Manufacturer | Published minimum | Notes |
|---|---|---|
| Jinher Nutra (Chino) | 1,500 bottles (custom, typical start) | Lower entry points for stock formulas |
| Superior Supplement Manufacturing (Fountain Valley) | Capsules: 150,000 capsules or 2,500 bottles of 60 | Capsule minimum as the company publishes it |
Minimums from each manufacturer's website (Jinher Nutra, Superior), read October 2026. Minimums change based on product type, ingredients, and current capacity. Confirm directly with the manufacturer before planning a production run.
Stock formulas (also called private label) let you start with very small quantities because the manufacturer already has the formula, ingredients, and production setup. Custom formulation requires dedicated ingredient sourcing and equipment configuration, which drives MOQs higher.
If you are testing a new product concept, consider starting with a stock formula to validate demand before investing in custom formulation. See our guide to supplement costs for detailed cost breakdowns by dosage form and volume tier, or use the First Run Cost Estimator for a rough budget estimate.
Every manufacturer listed below cites its sources, as our published assessment method requires. Where the issuing program publishes a registry, such as NSF's or USDA's, we check certifications against it. Certification statuses are marked as “confirmed” (independently checked against registry) or “self-reported” (claimed by the manufacturer but not yet independently confirmed).
If you are a manufacturer and your information needs updating, use our listing claim form.
CONTRACT MANUFACTURING
Chino, California
Contract manufacturer of vitamin, mineral, probiotic, amino acid, enzyme and herbal extract supplements.
MOQ
Not publicly disclosed
LEAD TIME
Not publicly disclosed
CONTRACT MANUFACTURING
Valencia, California
Manufacturer of capsules, tablets, powders and gummies with an in-house microbiology lab for emerging brands.
MOQ
2,500 units
LEAD TIME
8-10 weeks
CONTRACT MANUFACTURING
Santa Ana, California
High-volume maker of softgels, including vegetarian, plus tablets, capsules, gummies, powders and liquids.
MOQ
Not publicly disclosed
LEAD TIME
Not publicly disclosed
CONTRACT MANUFACTURING
City of Industry, California
Softgel manufacturer with gelatin, plant-based and enteric softgels, plus tablets, capsules and gummies.
MOQ
Not publicly disclosed
LEAD TIME
Not publicly disclosed
CONTRACT MANUFACTURING
Cerritos, California
Softgel and gummy manufacturer that developed a marine-sourced alternative to bovine and porcine gelatin.
MOQ
Not publicly disclosed
LEAD TIME
Not publicly disclosed
CONTRACT MANUFACTURING
Anaheim, California
Contract manufacturer of supplements and homeopathic drug products, offering blister card packaging.
MOQ
Not publicly disclosed
LEAD TIME
Not publicly disclosed
CONTRACT MANUFACTURING
Riverside, California
Contract manufacturer of capsules, tablets, powders and nutritional bars for sports and weight management.
MOQ
Not publicly disclosed
LEAD TIME
Not publicly disclosed
CONTRACT MANUFACTURING
Carlsbad, California
Private label contract manufacturer that also develops proprietary beta-alanine ingredients.
MOQ
Not publicly disclosed
LEAD TIME
Not publicly disclosed
CONTRACT MANUFACTURING
Ontario, California
Contract packager with high-speed bottling, powder blending, stick packing and in-house label printing.
MOQ
Not publicly disclosed
LEAD TIME
Not publicly disclosed
CONTRACT MANUFACTURING
Torrance, California
Maker of tablets, capsules and powders with in-house analytical and microbiological laboratories.
MOQ
Not publicly disclosed
LEAD TIME
Not publicly disclosed
CONTRACT MANUFACTURING
Commerce, California
Softgel specialist focused on oil-based formulas, including enteric-coated and delayed-release softgels.
MOQ
Not publicly disclosed
LEAD TIME
Not publicly disclosed
CONTRACT MANUFACTURING
Anaheim, California
Contract manufacturer of protein powders, pre-workout formulas and capsules in a solar-powered facility.
MOQ
Not publicly disclosed
LEAD TIME
Not publicly disclosed
CONTRACT MANUFACTURING
California
Full-service maker of capsules, tablets, softgels, powders and gummies, from pilot batches to commercial runs.
MOQ
Not publicly disclosed
LEAD TIME
Not publicly disclosed
CONTRACT MANUFACTURING
Chula Vista, California
Contract manufacturer of capsule, tablet, liquid and powder dietary supplements.
MOQ
Not publicly disclosed
LEAD TIME
Not publicly disclosed
CONTRACT MANUFACTURING
Corona, California
Contract manufacturer specializing in custom liquid supplements and dry-blended powder formulations.
MOQ
Not publicly disclosed
LEAD TIME
Not publicly disclosed
CONTRACT MANUFACTURING
Ontario, California
Full-scale supplement manufacturer packaging in bottles, jars, gusset bags, pouches, stick packs and tubes.
MOQ
Not publicly disclosed
LEAD TIME
Not publicly disclosed
CONTRACT MANUFACTURING
Fullerton, California
Softgel specialist offering softgel contract manufacturing, analytical testing and packaging.
MOQ
Not publicly disclosed
LEAD TIME
Not publicly disclosed
CONTRACT MANUFACTURING
Anaheim, California
Maker of nutritional bars and functional powders, with formulation and ingredient sourcing.
MOQ
Not publicly disclosed
LEAD TIME
Not publicly disclosed
CONTRACT MANUFACTURING
Brea, California
Capsule and powder manufacturer with custom formulation and private label services.
MOQ
Not publicly disclosed
LEAD TIME
Not publicly disclosed
CONTRACT MANUFACTURING
Rancho Cucamonga, California
Custom formulation and private label manufacturer of capsules, powders, softgels and tablets.
MOQ
Not publicly disclosed
LEAD TIME
Not publicly disclosed
CONTRACT MANUFACTURING
Vista, California
Private label maker of capsules, ingestible liquids, ingestible oils and powders with custom formulation.
MOQ
Not publicly disclosed
LEAD TIME
Not publicly disclosed
PACKAGING LABELING
Rancho Cucamonga, California
Packaging and assembly provider offering hand assembly, blister packaging, shrink wrapping and repack work.
MOQ
Not publicly disclosed
LEAD TIME
Not publicly disclosed
PACKAGING LABELING
Garden Grove, California
Contract packager for pouching, stick packs, sachets, blister packs and rigid container filling.
MOQ
Not publicly disclosed
LEAD TIME
Not publicly disclosed
PACKAGING LABELING
Oakland, California
Folding carton and label printer with in-house lithographic printing, die cutting and lamination.
MOQ
Not publicly disclosed
LEAD TIME
Not publicly disclosed
PACKAGING LABELING
San Dimas, California
Flexible packaging maker of custom printed stand-up and flat pouches and stick packs in high-barrier films.
MOQ
Not publicly disclosed
LEAD TIME
Not publicly disclosed
PACKAGING LABELING
Chatsworth, California
Vitamin and supplement label printer using digital and flexographic printing on a dedicated label line.
MOQ
Not publicly disclosed
LEAD TIME
Not publicly disclosed
PACKAGING LABELING
San Marcos, California
Supplement packager offering bottling, supplement packets and powder packaging.
MOQ
Not publicly disclosed
LEAD TIME
Not publicly disclosed
PACKAGING LABELING
Vista, California
Manufacturer and packager offering bottle filling, stick pack filling, shrink sleeves and label application.
MOQ
Not publicly disclosed
LEAD TIME
Not publicly disclosed
PACKAGING LABELING
Santa Fe Springs, California
Contract manufacturer and packager offering encapsulation, bottling, powder filling and in-house testing.
MOQ
Not publicly disclosed
LEAD TIME
Not publicly disclosed
PACKAGING LABELING
Ontario, California
Contract manufacturer and packager of capsules, tablets, powders, gummies and softgels with label design.
MOQ
Not publicly disclosed
LEAD TIME
Not publicly disclosed
PACKAGING LABELING
Los Angeles, California
Contract packager offering blister and bottle packaging, formulating and blending for capsules and powders.
MOQ
Not publicly disclosed
LEAD TIME
Not publicly disclosed
PACKAGING LABELING
Tracy, California
Family-owned packager offering toll blending, co-manufacturing, stick packing and bottling.
MOQ
Not publicly disclosed
LEAD TIME
Not publicly disclosed
PACKAGING LABELING
Chula Vista, California
Contract manufacturer offering encapsulation, tableting, coatings and liposomal delivery systems.
MOQ
Contact for quote
LEAD TIME
Contact for quote
PACKAGING LABELING
Stanton, California
Contract manufacturer and packager offering blending, encapsulation and bottle, blister and powder packaging.
MOQ
Contact for quote
LEAD TIME
Contact for quote
PACKAGING LABELING
Anaheim, California· est. 2014
Supplement and sports nutrition contract manufacturer with co-packing and custom formulation.
MOQ
Contact for quote
LEAD TIME
Contact for quote
FLAVOR DEVELOPMENT
Commerce, California
Wholesale flavor and color maker with masking agents and sweetness enhancers for supplements.
MOQ
Not publicly disclosed
LEAD TIME
Not publicly disclosed
FLAVOR DEVELOPMENT
Benicia, California
Flavor manufacturer making powder, liquid, plated and spray-dried flavors with pilot-scale spray dryers.
MOQ
Not publicly disclosed
LEAD TIME
Not publicly disclosed
FLAVOR DEVELOPMENT
El Cajon, California
Flavor subsidiary specializing in flavor masking and bitter blockers for vitamins, oils and caffeine.
MOQ
Not publicly disclosed
LEAD TIME
Not publicly disclosed
FLAVOR DEVELOPMENT
Cerritos, California
North American arm of a global flavor maker, specializing in flavor modulation and masking.
MOQ
Not publicly disclosed
LEAD TIME
Not publicly disclosed
FLAVOR DEVELOPMENT
Norco, California
Family-owned flavor maker developing custom liquid and powder flavors in-house for nutraceuticals.
MOQ
Not publicly disclosed
LEAD TIME
Not publicly disclosed
FLAVOR DEVELOPMENT
Santa Ana, California
Family-owned maker of custom beverage and food flavors with in-house manufacturing.
MOQ
Not publicly disclosed
LEAD TIME
Not publicly disclosed
FLAVOR DEVELOPMENT
Riverside, California
Custom flavor maker for nutraceuticals and vitamins, including powdered flavors for protein powders.
MOQ
Not publicly disclosed
LEAD TIME
Not publicly disclosed
FLAVOR DEVELOPMENT
Commerce, California
Flavor and fragrance maker supplying custom liquid and powder flavors for sports nutrition products.
MOQ
Not publicly disclosed
LEAD TIME
Not publicly disclosed
INGREDIENT SUPPLIERS
Fullerton, California
Ingredient distributor with in-house blending, granulation, milling and instantizing services.
MOQ
Not publicly disclosed
LEAD TIME
Not publicly disclosed
INGREDIENT SUPPLIERS
Montclair, California
Maker of citrus flavonoid and bioflavonoid ingredients, plus custom probiotic blends.
MOQ
Not publicly disclosed
LEAD TIME
Not publicly disclosed
INGREDIENT SUPPLIERS
City of Industry, California
Specialty ingredient company supplying branded ingredients to supplement brands.
MOQ
Not publicly disclosed
LEAD TIME
Not publicly disclosed
INGREDIENT SUPPLIERS
Ventura, California
Maker of chelated minerals, vitamin C ingredients and omega powders sourced from fish, algae and flaxseed.
MOQ
Not publicly disclosed
LEAD TIME
Not publicly disclosed
INGREDIENT SUPPLIERS
Los Angeles, California
Bioscience company supplying nicotinamide riboside, a patented NAD precursor ingredient.
MOQ
Not publicly disclosed
LEAD TIME
Not publicly disclosed
INGREDIENT SUPPLIERS
Walnut Creek, California
US office of a Japanese lab supplying nattokinase fermented with a patented strain.
MOQ
Not publicly disclosed
LEAD TIME
Not publicly disclosed
TESTING LABS
Garden Grove, California
Botanical and mushroom testing lab focused on identity and potency analysis using HPTLC and microscopy.
LEAD TIME
Not publicly disclosed
TESTING LABS
Irvine, California
Supplement and cosmetic testing lab covering identity, potency, pesticides and preservative efficacy.
LEAD TIME
48 hours for standard panels
TESTING LABS
San Francisco, California
Family-owned analytical testing company offering identity, potency, contaminant and microbiological testing.
LEAD TIME
Not publicly disclosed
FORMULATION RD
Irvine, California
Formulation consultancy offering ingredient sourcing, regulatory guidance and stability study coordination.
MOQ
Project-based (consulting)
LEAD TIME
Not publicly disclosed
REGULATORY COMPLIANCE
Carlsbad, California
Regulatory consulting firm specializing in NDI notifications, labeling and regulatory strategy.
LEAD TIME
Not publicly disclosed
Dietary supplement manufacturers must comply with 21 CFR Part 111 (Current Good Manufacturing Practice for dietary supplements). This includes requirements for personnel, facilities, equipment, production, laboratory operations, and record-keeping.
Yes. California's Proposition 65 (the Safe Drinking Water and Toxic Enforcement Act of 1986) requires businesses with 10 or more employees to warn consumers about significant exposures to chemicals that cause cancer or reproductive harm. OEHHA publishes safe-harbor levels: lead (0.5 mcg/day MADL, reproductive), cadmium (4.1 mcg/day oral MADL, reproductive), inorganic arsenic compounds (10 mcg/day NSRL for routes other than inhalation, cancer), and mercury (no safe-harbor level on OEHHA's list, evaluate on a per-product basis). 21 CFR Part 111 sets no numeric limits for these metals: it requires each manufacturer to set its own limits on contamination (21 CFR 111.70(e)), so a product that meets its Part 111 specifications can still need a Prop 65 warning.
A Processed Food Registration (PFR) is the California Department of Public Health's basic health permit. Health and Safety Code section 110460 requires businesses that manufacture, repack, label, or warehouse processed food in California to register, and CDPH lists dietary supplements among the products it covers. It is separate from federal FDA food facility registration. If your manufacturer, packer, or labeler is in California, ask for its current PFR.
The published minimums of two California manufacturers sit close together. Jinher Nutra says its custom runs typically start at 1,500 bottles, with lower entry points for its stock formulas. Superior Supplement Manufacturing gives its capsule minimum as 150,000 capsules or 2,500 bottles of 60. Minimums change with the product, so confirm with each manufacturer. If you are testing a new product, ask about stock formulas or small custom runs before committing to a large run.
At minimum: FDA food facility registration (21 CFR 1.225, unless a 21 CFR 1.226 exemption applies) and cGMP compliance under 21 CFR Part 111 are legally required. Beyond that, third-party GMP programs, such as NSF's GMP registration, add an outside audit. NSF Certified for Sport or Informed Sport matter if your products target athletes. Organic (USDA NOP) or Non-GMO Project verification apply to specific product claims. Check our certification pages for details on what each certification proves and does not prove.
There is no single answer. A manufacturer's own costs and how much of them reach your quote vary by company, so compare quotes for the same formula, count, and quantity rather than assume a California premium or discount. California puts you near the Ports of Long Beach and Los Angeles and inside the most populous US state. Whether that is worth it depends on your supply chain and where your customers are.
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Every listing cites its sources.